Kim Navarrete, MSN, APRN, FNP-C, OCN, and Nilesh Kalariya, PhD, AGPCNP-BC, AOCNP Multiple myeloma (MM) is a hematologic malignancy associated with the clonal proliferation of plasma cells. Despite decades of…
Karla V. Ow, MSN, FNP, AOCNP Chimeric antigen receptor (CAR) T cells are lymphocytes that have been genetically modified to produce a CAR that specifically targets tumor cell antigens.1 CAR…
Nilesh Kalariya, PhD, AGPCNP-BC, AOCNP The Food and Drug Administration approved Carvykti (ciltacabtagene autocleucel, Janssen Biotech Inc.) in February 2022 making it the second chimeric antigen receptor (CAR) T-cell therapy…
Amanda Y. Tam, MS, FNP-BC The standard of care with curative intent for resectable or borderline resectable pancreatic adenocarcinoma involves surgery and then adjuvant chemotherapy. High-risk features include the following:…
Lucia Diaz, DNP, ANP-BC, CUNP It is estimated that between 19% and 100% of patients receiving antineoplastic medications known to cause neuropathy may develop chemotherapy-induced peripheral neuropathy (CIPN)1, which may…
Taylor A. Aldridge, MMS, PA-C Pancreatic ductal adenocarcinoma (PDAC) is a notoriously aggressive gastrointestinal malignancy with an overall 5-year survival rate of 5%.1 This grim prognosis is primarily due to…
The Oncology Connection Fam-trastuzumab-deruxtecan-nxki (Enhertu, Daiichi-Sankyo/AstraZeneca), or T-DXd, led to a high intracranial response rate in patients with active brain metastases from human epidermal growth factor receptor 2 (HER2)-positive breast…
Sijimol Mathew, DNP, APRN The patient with cancer has many risk factors for developing lactic acidosis. The diagnosis of cancer itself contributes to the overproduction of lactate caused by thiamine…
Beth Sandy, MSN, CRNP Proton pump inhibitors (PPIs) are very common to use in a wide variety of patients to treat many different symptoms of anything from a more serious…
Glen J Peterson, RN, DNP, ACNP and Jessica Casselberry, MSN, ANP-BC, AOCNP A thorough assessment of the patient with a hematologic malignancy is essential for the delivery of quality care.…